Attenuated measles virus as a vaccine vector
نویسندگان
چکیده
منابع مشابه
Experimental study of a further attenuated live measles vaccine of the Sugiyama strain in Iran
متن کامل
Mucosal DNA vaccine immunization against measles with a highly attenuated Shigella flexneri vector.
An intranasal vaccine vector would elicit protective immunity at the respiratory mucosa, the portal of entry and the primary site for replication for measles virus (MV) and other respiratory viruses. In a murine model of pulmonary Shigella, we demonstrate here that a candidate-attenuated Shigella vaccine vector is safely tolerated in IFN-gamma deficient mice at an inoculum that is 1 million-fol...
متن کاملA highly attenuated measles virus vaccine strain encodes a fully functional C protein.
The P, V, and C proteins of measles virus are encoded in overlapping reading frames of the P gene, which makes it difficult to analyze the functions of the individual proteins in the context of virus infection. We established a system to analyze the C protein independently from the P and V proteins by placing its gene in an additional transcription unit between the H and L genes. Analyses with ...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2007
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2007.01.064